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  Bioactive Constituents from Genus Otostegia

Shafiullah Khan1* and Fatima Syed2

1 Department of Chemistry, Gomal University, Dera Ismail Khan, KPK, Pakistan.                                   2 Institute of Chemical Science, University of Peshawar, KPK, Pakistan.

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Abstract

Present review describes research on structures, origins, novel natural biologically active compounds isolated from Genus Otostegia, which is major source of pharmacologically active substances. There are above 20 species. Many of these species have circumboreal distribution in Mediterranean region and Asia. Only a small number of the most common species with the most obvious fruiting bodies have been evaluated for biological activity. There are more than 65 new and novel compounds have been isolated. The purpose of this article is to be present a structurally reviewed some pharmacologically important of novel naturally presented chemical compounds isolated from a wide variety of different species of this genus. Naturally, the species of this genus traditionally been used as an ophthalmia, mosquito repellency, antimicrobial activity, antihyperglyceamic activity and antioxidant activity which prevent different kind of ailment. This review will present some of the aspects of the medicinal chemistry developed recently and complete list of constituents and sources along with reference.

Keywords: Otostegia, Pharmacological Activity, Chemical Constituent, Structures

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